3,5-Difluorophenol CAS 2713-34-0: Properties, Uses, and Sourcing Guide

3,5-Difluorophenol, identified by CAS Registry Number 2713-34-0, is a fluorinated aromatic phenol used primarily as a building block for pharmaceutical, agrochemical, and specialty chemical synthesis. Its molecular formula is C₆H₄F₂O, and its listed molecular weight is 130.09 g/mol. At Maison Chemical, I support B2B buyers by helping them evaluate identity, quality requirements, documentation, packaging, and delivery conditions before they place an order.

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Who This Guide Is For

This guide is intended for procurement teams, process chemists, R&D groups, pharmaceutical intermediate manufacturers, and distributors evaluating 3,5-Difluorophenol for laboratory or production use. It is also useful for buyers comparing supplier quotations where the product name is the same but the specification, packaging, analytical documentation, or delivery terms may differ. I focus here on practical sourcing decisions rather than making unsupported claims about a specific synthesis route or end product.

What Is 3,5-Difluorophenol?

3,5-Difluorophenol is a substituted phenol in which two fluorine atoms occupy the 3 and 5 positions of the aromatic ring relative to the hydroxyl group. The phenolic hydroxyl group provides a reactive functional handle, while the fluorine substituents modify the electronic and physical properties of the aromatic structure. These characteristics make the compound relevant as a synthetic intermediate when a fluorinated phenolic motif is required.

The product should not be evaluated only by its common name. A complete technical review should confirm the CAS number, molecular formula, molecular weight, appearance, assay or purity method, water content where relevant, residual solvents, and the intended storage conditions. For regulated or quality-sensitive projects, I also recommend reviewing the current Safety Data Sheet and Certificate of Analysis before approving a supplier.

Basic Identification Data

Properties and Technical Considerations

The aromatic ring and phenolic group determine much of the compound’s chemical behavior, while the two fluorine atoms influence electron distribution and substitution patterns. In practical development work, these features can affect reaction selection, conversion, purification, and compatibility with downstream intermediates. Exact behavior should be confirmed under the buyer’s own process conditions because solvent, temperature, concentration, catalysts, and reaction scale can change performance.

3,5-Difluorophenol should be handled as a specialty chemical rather than as a general-purpose commodity. The relevant safety profile depends on concentration, route of exposure, workplace controls, and the specific formulation or mixture. I recommend using the supplier’s current SDS, applying suitable local ventilation and personal protective equipment, and requiring a formal hazard review before laboratory or plant use.

Specification Items Buyers Should Review

• Identity: Confirm CAS 2713-34-0 and verify the identity method stated on the analytical documentation.
• Assay or purity: Define the minimum acceptable value and the analytical method, such as a validated chromatographic method where applicable.
• Appearance: Request a clear description of the expected physical appearance and acceptable variation.
• Water and residual solvents: Include these tests when they may affect reaction yield, stability, or downstream purification.
• Impurity profile: Identify critical impurities based on the planned synthesis and regulatory requirements.
• Packaging: Confirm the container material, net quantity, labeling, and protection from unsuitable storage conditions.

Applications and Application Matching

The principal value of 3,5-Difluorophenol is its use as a fluorinated aromatic starting material or intermediate. It may be considered in routes involving phenolic derivatization, aromatic substitution, coupling, or the preparation of more structurally complex research compounds. The exact application depends on the buyer’s synthetic route, required impurity limits, scale, and downstream purification strategy.

In pharmaceutical research, fluorinated building blocks are often screened when researchers are modifying molecular properties during lead development. However, the presence of a fluorinated phenol does not by itself prove suitability for a particular active pharmaceutical ingredient or process. Buyers should evaluate route-specific reactivity, analytical control, toxicological requirements, and the status of the resulting intermediate within their own quality system.

Agrochemical and specialty chemical developers may also assess this material when a fluorinated phenolic fragment is needed. For these projects, the most important purchasing questions often include lot consistency, reliable analytical data, scalability, and the supplier’s ability to maintain the agreed specification over repeat orders. A small laboratory sample and a production lot should be compared before long-term supply approval.

How to Select the Right Material and Supplier

Step 1: Define the Intended Use

Start by distinguishing among screening, route development, pilot production, and routine manufacturing. A research project may accept a broader specification during early experimentation, while commercial production generally requires tighter control of impurities, documentation, change notification, and lot-to-lot consistency. This first decision prevents buyers from comparing quotations that are not technically equivalent.

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Step 2: Create a Written Specification

Specify the required purity, analytical method, packaging, storage expectations, and documentation before requesting offers. If a particular impurity is critical to your process, list it separately instead of relying only on a general assay value. I can review these requirements with the buyer so that the commercial quotation reflects the actual technical need.

Step 3: Request a Representative Documentation Package

Before purchase, request the product specification, recent or representative COA, SDS, and packaging information. For regulated supply chains, buyers may also need country-of-origin information, lot traceability, change-control procedures, and other documents required by their internal quality system. Documentation should be reviewed for consistency with the product name, CAS number, lot number, test dates, and stated methods.

Step 4: Confirm Logistics and Commercial Terms

Ask for the available package size, minimum order quantity, production or release lead time, shipping route, Incoterms, and quotation validity. Lead time is not a fixed property of the chemical; it can vary according to stock status, batch scheduling, quality release, packaging, and destination requirements. For this reason, I provide delivery discussions on a case-by-case basis rather than presenting an unsupported universal lead-time promise.

Pricing, MOQ, and Lead-Time Factors

The price of 3,5-Difluorophenol can depend on purity target, order quantity, packaging format, testing requirements, and shipping destination. A lower unit price may not represent the lower total procurement cost if it requires excessive inventory, additional testing, or unsuitable packaging. Buyers should compare the full delivered cost and the risk of supply interruption, not only the quoted price per kilogram.

Minimum order quantity is also project-dependent. Laboratory quantities, development batches, and commercial volumes may be handled through different packaging and production arrangements. When I prepare a quotation at Maison Chemical, I ask for the target quantity, destination, specification, and expected purchasing frequency so that the offer can be aligned with the actual requirement.

Common Sourcing Mistakes

• Ordering by product name alone without confirming CAS 2713-34-0.
• Comparing purity values without checking whether the analytical methods are equivalent.
• Accepting a generic SDS without verifying that it applies to the supplied product and concentration.
• Ignoring packaging, transport, storage, and labeling requirements until after the order is placed.
• Approving a supplier from one successful sample without assessing repeat-lot documentation and communication.
• Assuming that a research-grade material automatically meets a manufacturing or regulatory specification.

How Maison Chemical Supports B2B Buyers

Maison Chemical supplies 3,5-Difluorophenol CAS 2713-34-0 for customers evaluating pharmaceutical intermediates, research compounds, and specialty chemical applications. I can help clarify product identification, specification alignment, packaging options, documentation requirements, and shipment planning. The final offer depends on the requested grade, quantity, destination, and current availability.

For a more efficient quotation, send the required quantity, target purity, intended application, destination country, preferred packaging, and any document requirements. If your project is still in development, I can also help separate essential specifications from optional tests so that the purchasing process remains technically appropriate and commercially practical.

Key Takeaways

• 3,5-Difluorophenol is a fluorinated aromatic phenol with CAS 2713-34-0, formula C₆H₄F₂O, and molecular weight 130.09 g/mol.
• Its main B2B role is as a synthetic intermediate for pharmaceutical, agrochemical, and specialty chemical development.
• Supplier evaluation should cover identity, purity, impurity control, documentation, packaging, logistics, and repeat-lot consistency.
• MOQ, price, and lead time should be confirmed against the buyer’s specification and destination rather than assumed from a generic listing.

Conclusion: Is 3,5-Difluorophenol Right for Your Project?

3,5-Difluorophenol CAS 2713-34-0 is a relevant choice when your synthesis requires a defined difluorinated phenolic building block. The correct purchasing decision depends on route compatibility, required purity, analytical controls, handling procedures, and dependable supply documentation. It should be approved against your own process and quality requirements rather than selected on name or price alone.

The next step is to prepare a concise purchasing specification and request a quotation with the required quantity, purity, packaging, destination, and documentation. Contact Maison Chemical with those details, and I will help you evaluate the supply option for your development or manufacturing plan.

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